Coenzyme Q10


Coenzyme Q10 (Co Q10)is a strong antioxidant and is an essential ingredient      in the body’s production of energy and in the normal metabolism of fat      and energy. It participates in biochemical reactions in our bodies that      provide energy. Scientists have long believed that Co Q10 produces beneficial   effects to the heart,1-5 brain,1,6 kidneys,1,7 and  other tissues.8-9

Co Q10 levels are reported to decrease with age and to be low in persons      with some chronic diseases such as heart conditions, muscular dystrophies,      Parkinson’s disease, cancer, diabetes, and HIV/AIDS. Some prescription      drugs may also lower Co Q10 levels. Depending on the cause of Co Q10 deficiency,      supplementation or increased dietary intake of Co Q10 and the vitamins      and minerals needed to produce Co Q10 may be effective.

A growing body of research suggests that using Co Q10 supplements alone      or in combination with other drug therapies and nutritional supplements      may help prevent or treat a variety of heart diseases including high blood      pressure10. Researchers believe that the beneficial      effect of CoQ10 in the prevention and treatment of heart disease is due      to its ability to improve energy production in cells, inhibit blood clot      formation, and its activity as a powerful antioxidant. A growing number      of nutrition oriented doctors say that supplements of Co Q10 are absolutely      essential for people with a variety of heart diseases, including cardiac   failure.

These statements have not been evaluated by the U.S.  Food and Drug Administration.
These products are not intended to diagnose, cure or prevent any disease.
1.  Dhanasekaran            M, Ren J. The emerging role of coenzyme Q-10 in aging, neurodegeneration,            cardiovascular disease, cancer and diabetes mellitus. Curr Neurovasc            Res 2005;2(5):447-59.             2.  Rosenfeldt FL, Pepe S, Linnane A, et al. Coenzyme Q10 protects            the aging heart against stress: studies in rats, human tissues, and            patients. Ann NY Acad Sci. 2002 Apr;959:355-9.             3.  Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD. Coenzyme            Q10 improves blood pressure and glycaemic control: a controlled trial            in subjects with type 2 diabetes. Eur J Clin Nutr. 2002 Nov;56(11):1137-42.             4.  Greenberg S, Frishman WH. Co-enzyme Q10: a new drug for            cardiovascular disease. J Clin Pharmacol. 1990 Jul;30(7):596-608.             5.  Thomas SR, Leichtweis SB, Pettersson K, et al. Dietary cosupplementation            with vitamin E and coenzyme Q(10) inhibits atherosclerosis in apolipoprotein            E gene knockout mice. Arterioscler Thromb Vasc Biol. 2001 Apr;21(4):585-93. 6.  Matthews RT,            Yang L, Browne S, Baik M, Beal MF. Coenzyme Q10 administration increases            brain mitochondrial concentrations and exerts neuroprotective effects.            Proc Natl Acad Sci USA. 1998 Jul 21;95(15):8892-7.             7.  Gazdikova K, Gvozdjakova A, Kucharska J et al. [Effect of            coenzyme Q10 in patients with kidney diseases]. Cas Lek Cesk. 2001            May 24;140(10):307-310.             8.  Feher J, Kovacs B, Kovacs I, et al. Improvement of visual            functions and fundus alterations in early age-related macular degeneration            treated with a combination of acetyl-L-carnitine, n-3 fatty acids,            and coenzyme Q10. Ophthalmologica. 2005 May;219(3):154-66.             9.  Quiles JL, Farquharson AJ, Ramirez-Tortosa MC, et al. Coenzyme            Q differentially modulates phospholipid hydroperoxide glutathione            peroxidase gene expression and free radicals production in malignant            and non-malignant prostate cells. Biofactors. 2003;18(1-4):265-70.             10.  Rosenfeldt FL, Haas SJ, Krum H, Hadj A, Ng K, Leong J-Y,            Watts GF. Coenzyme Q10 in the treatment of hypertension: a meta-analysis            of the clinical trials. J Human Hypertension 21: 297-306, 2007.

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